Handelsman Lab

Microbiology Publications in 1990s


Stohl, E.A., Milner, J.L., and Handelsman, J. 1999. Zwittermicin A biosynthetic cluster. Gene 237: 403-411.

Stohl, E.A., Brady, S.F., Clardy, J., and Handelsman, J. 1999. ZmaR, a novel and widespread antibiotic resistance determinant that acetylates zwittermicin A. J. Bacteriol. 181: 5455-5460.

Raffel, S.J., Kazmar, E.R, Winberg, R., Oplinger, E.S., Handelsman, J., Goodman, R.M., and Grau, C.R. 1999. First report of root rot of soybeans caused by Corynespora cassiicola in Wisconsin. Plant Dis. 83: 696.

Rondon, M.R., Raffel, S.J., Goodman, R.M., and Handelsman, J. 1999. Toward functional genomics in bacteria: Analysis of gene expression in Escherichia coli from a bacterial artificial chromosome library of Bacillus cereus. Proc. Natl. Acad. Sci. USA 96: 6451-6455.

Smith, K.P., Handelsman, J., and Goodman, R.M. 1999. Genetic basis in plants for interactions with disease-suppressive bacteria. Proc. Natl. Acad. Sci. USA 96: 4786-4790.

Shang, H., Chen, J.-J., Handelsman, J., and Goodman, R.M. 1999. Behavior of Pythium torulosum zoospores during their interaction with tobacco roots and Bacillus cereus. Current Microbiol. 38: 199-204.

Dunn, A.K., and Handelsman, J. 1999. A vector for promoter trapping in Bacillus cereus. Gene 226: 297-305.

Emmert, E.A.B., and Handelsman, J. 1999. Biocontrol of plant disease: a (Gram-) positive perspective. FEMS Microbiology Letters 171: 1-9.

Rondon, M.R., Goodman, R.M., and Handelsman, J. 1999. The Earth’s bounty: assessing and accessing soil microbial diversity. Trends in Biotechnology 17: 403-409.


Handelsman, J., Rondon, M.R., Brady, S., Clardy, J., and Goodman, R.M. 1998. Molecular biology access to the chemistry of unknown soil microbes: a new frontier for natural products. Chemistry & Biology 5: R245-R249.

Goodman, R.M., Bintrim, S.B., Handelsman, J., Quirino, B.F., Rosas, J.C., Simon, H.M., and Smith, K.P. 1998. A dirty look: soil microflora and rhizosphere microbiology. In: Radical Biology: Advances and Perspectives on the Function of Plant Roots. H.E. Flores, J.P. Lynch, and D. Eissenstat, eds. Rockville, MD: Amer. Soc. Plant Physiol. Press, pp. 219-231.

Emmert, E.A.B., Milner, J.L., Lee, J.C., Pulvermacher, K.L., Olivares, H.A., Clardy, J., and Handelsman, J. 1998. Effect of canavanine from alfalfa seeds on the population biology of Bacillus cereus. Appl. Environ. Microbiol. 64: 4683-4688.

Rosas, J.C., Castro, J.A., Robleto, E.A., and Handelsman, J. 1998. A method for screening Phaseolus vulgaris L. germplasm for preferential nodulation with a selected Rhizobium etli strain. Plant and Soil 203: 71-78.

O’Connell, K.P., Raffel, S.J., Saville, B.J., and Handelsman, J. 1998. Mutants of Rhizobium tropici strain CIAT899 that do not induce chlorosis in plants. Microbiology 144: 2607-2617.

Biermann, B.J., de Banzie, J.S., Handelsman, J., Thompson, J.F., and Madison, J.T. 1998. Methionine and sulfate increase a Bowman-Birk-type protease inhibitor and its messenger RNA in soybeans. J. Agric. Food Chem. 46: 2858-2862.

Silo-Suh, L.A., Stabb, E.V., Raffel, S.J., and Handelsman, J. 1998. Target range of zwittermicin A, an aminopolyol antibiotic from Bacillus cereus. Current Microbiology 37: 6-11.

Stabb, E.V., and Handelsman, J. 1998. Genetic analysis of zwittermicin A resistance in Escherichia coli: effects on membrane potential and RNA polymerase. Molecular Microbiology 27: 311-322.


Bintrim, S.B., Donohue, T.J., Handelsman, J., Roberts, G.P., and Goodman, R.M. 1997. Molecular phylogeny of Archaea from soil. Proc. Natl. Acad. Sci. 94: 277-282.

Smith, K.P., Handelsman, J., and Goodman, R.M. 1997. Modeling dose-response relationships in biological control: partitioning host responses to the pathogen and biocontrol agent. Phytopathology 87: 720-729.

Bittinger, M.A., Milner, J.L., Saville, B.J., and Handelsman, J. 1997. rosR, a determinant of nodulation competitiveness in Rhizobium etli. Mol. Plant-Microbe Interact. 10: 180-186.

Milner, J., Silo-Suh, L., Goodman, R.M., and Handelsman, J. 1997. Antibiosis and beyond: Genetic diversity, microbial communities, and biological control. In: Ecological Interactions and Biological Control. D.A. Andow, D.W. Ragsdale, and R.F. Nyvall, eds. Minneapolis, MN, pp. 107-127.


O’Connell, K.P., Goodman, R.M., and Handelsman, J. 1996. Engineering the rhizosphere: Expressing a bias. Trends in Biotechnology 14: 83-88.

Handelsman, J., and Stabb, E.V. 1996. Biocontrol of soilborne plant pathogens. Plant Cell 8: 1855-1869.

Raffel, S.J., Stabb, E.V., Milner, J.L., and Handelsman, J. 1996. Genotypic and phenotypic analysis of zwittermicin A-producing strains of Bacillus cereus. Microbiology 142: 3425-3436.

Milner, J.L., Silo-Suh, L., Lee, J.C., He, H., Clardy, J., and Handelsman, J. 1996. Production of kanosamine by Bacillus cereus UW85. Appl. Environ. Microbiol. 62: 3061-3065.

Gilbert, G.S., Clayton, M.K., Handelsman, J., and Parke, J.L. 1996. Use of cluster and discriminant analyses to compare rhizosphere bacterial communities. Microbial Ecology 32: 123-147.

Milner, J.L., Stohl, E.A., and Handelsman, J. 1996. Zwittermicin A resistance gene from Bacillus cereus. J. Bacteriol. 178: 4266-4272.

Chen, J., Jacobson, L.M., Handelsman, J., and Goodman, R.M. 1996. Compatibility of systemic acquired resistance and microbial biocontrol for suppression of plant disease in a laboratory assay. Molecular Ecology 5: 73-80.


Milner, J.L., Raffel, S.J., Lethbridge, B.J., and Handelsman, J. 1995. Culture conditions that influence accumulation of zwittermicin A by Bacillus cereus UW85. Applied Microbiol. Biotechnol. 43: 685-691.

Osburn, R.M., Milner, J.L., Oplinger, E.S., Smith, R.S., and Handelsman, J. 1995. Effect of Bacillus cereus UW85 on the yield of soybean at two field sites in Wisconsin. Plant Dis. 79: 551-556.


Stabb, E.V., Jacobson, L., and Handelsman, J. 1994. Zwittermicin A-producing strains of Bacillus cereus from diverse soils. Appl. Environ. Microbiol. 60: 4404-4412.

Silo-Suh, L.A., Lethbridge, B.J., Raffel, S.J., He, H., Clardy, J., and Handelsman, J. 1994. Biological activities of two fungistatic antibiotics produced by Bacillus cereus UW85. Appl. Environ. Microbiol. 60: 2023-2030.

Araujo, R.S., Robleto, E.A., and Handelsman, J. 1994. A hydrophobic mutant of Rhizobium etli altered in nodulation competitiveness and growth in the rhizosphere. Appl. Environ. Microbiol. 60: 1430-1436.

He, H., Silo-Suh, L.A., Handelsman, J., and Clardy, J. 1994. Zwittermicin A, an antifungal and plant protection agent from Bacillus cereus. Tetrahedron Letters 35: 2499-2502.

Gilbert, G.S., Handelsman, J., and Parke, J.L. 1994. Root camouflage and disease control. Phytopathology 84: 222-225.


O’Connell, K.P., and Handelsman, J. 1993. Foliar chlorosis in symbiotic host and non-host plants induced by Rhizobium tropici type B strains. Appl. Environ. Microbiol. 59: 2184-2189.

Halverson, L.J., Clayton, M.K., and Handelsman, J. 1993. Variable stability of antibiotic resistance markers in Bacillus cereus UW85 in the soybean rhizosphere in the field. Molecular Ecology 2: 65-78.

Halverson, L.J., Clayton, M.K., and Handelsman, J. 1993. Population biology of Bacillus cereus UW85 in the rhizosphere of field-grown soybeans. Soil Biol. Biochem. 25: 485-493.

Beattie, G.A., and Handelsman, J. 1993. Evaluation of a strategy for identifying nodulation competitiveness genes in Rhizobium leguminosarum biovar phaseoli. J. Gen. Microbiol. 139: 529-538.

Smith, K.P., Havey, M.J., and Handelsman, J. 1993. Suppression of cottony leak of cucumber with Bacillus cereus strain UW85. Plant Dis. 77: 139-142.

Gilbert, G.S., Parke, J.L., Clayton, M.K., and Handelsman, J. 1993. Effects of an introduced bacterium on bacterial communities on roots. Ecology 74: 840-854.


Milner, J.L., Araujo, R.S., and Handelsman, J. 1992. Molecular and symbiotic characterization of exopolysaccharide-deficient mutants of Rhizobium tropici strain CIAT899. Molecular Microbiol. 6: 3137-3147.


Halverson, L.J., and Handelsman, J. 1991. Enhancement of soybean nodulation by Bacillus cereus UW85 in the field and in a growth chamber. Appl. Environ. Microbiol. 57: 2767-2770.

Handelsman, J., Nesmith, W.S., and Raffel, S.J. 1991. Microassay for biological and chemical control of infection of tobacco by Phytophthora parasitica var. nicotianae. Current Microbiol. 22: 317-319.


O’Connell, K.P., Araujo, R.S., and Handelsman, J. 1990. Exopolysaccharide deficient mutants of Rhizobium strain CIAT899 induce chlorosis in beans. Molec. Plant Microbe Interact. 3: 424 428.

Handelsman, J., Raffel, S., and Sequeira, L. 1990. Monoclonal antibodies against Agrobacterium tumefaciens strain C58. Current Microbiol. 21: 181-185.

Handelsman, J., Raffel, S.J., Mester, E.H., Wunderlich, L., and Grau, C.R. 1990. Biological control of damping off of alfalfa seedlings by Bacillus cereus UW85. Appl. Environ. Microbiol. 56: 713 718.

Gilbert, G.S., Handelsman, J., and Parke, J.L. 1990. Role of ammonia and calcium in lysis of zoospores of Phytophthora cactorum by Bacillus cereus UW85. Exper. Mycol. 14: 1 8.